What Is Carpenter Syndrome?

Carpenter syndrome is a rare genetic condition involving craniosynostosis. Here is an overview.

Carpenter syndrome (also called acrocephalopolysyndactyly type II) is a rare genetic condition characterized by craniosynostosis, facial features, and limb abnormalities.

  • Key features:
  • Craniosynostosis (fusion of multiple skull sutures)
  • Flat nasal bridge
  • Low-set, malformed ears
  • Heart defects (in some cases)
  • Short stature
  • Obesity (develops in childhood)
  • Intellectual disability (variable)
  • Polysyndactyly (extra and fused fingers/toes)

Cleft Lip Schematic
  • Treatment:
  • Skull surgery in infancy to relieve pressure
  • Hand surgery to separate fused digits
  • Heart evaluation and treatment (if needed)
  • Ongoing monitoring for obesity
  • Educational support

Clinical Guidance

Carpenter syndrome is a rare condition with craniosynostosis, obesity, developmental delay, and limb differences requiring multidisciplinary care and multiple surgeries.